Optical trapping inside cells shows that the dynein motor uses a nanoscale gear to distribute load equitably within a team of dyneins hauling a cargo. This allows large and precisely tunable collective forces to be generated by dynein-teams.... published in Cell. Read more...

The brain centers that control defensive/aggressive behaviours are formed in a different manner from those controlling reproductive behaviours.... published in Nature Neuroscience. Read more.... Further reading.

Early stress experience evokes both adaptive as well as maladaptive changes that emerge in a temporally regulated manner, with early adaptive outcomes that may eventually exert a high cost, evoking maladaptive consequences.... published in Biological Psychiatry. Read more...

An optical trapping method to precisely measure the force generated by motor proteins on single organelles of unknown size in cell extract... published in Nature Methods. Read more...

Drosophila Sir2 is necessary for life span extension in response to dietary restriction and that its overexpression in the fat body increases the life span... published in Cell Reports. Read more...

Arrest of malaria parasite cell division is observed through blockage of erythrocyte surface localized Plasmodium ribosomal protein P2... published in PLOS Pathogens. Read more...