Welcome to the Molecular Parasitology Lab

Malaria is a widespread tropical disease which has re-surged back in several parts of the world. It is estimated that about 200-300 million people get infected with malaria and about 0.9 million die annually. Caused by the unicellular protozoan parasites (Plasmodium species), the disease manifestations are largely linked to the growth of the parasite inside infected red blood cells.

The major challenges towards the control of malaria disease are a) a lack of effective vaccines; b) drug resistance; c) vector (mosquito) control and d) sanitation and medical management of the disease. In TIFR, our studies on the biology of the host-malarial parasite interactions are in the following specific lines of research:

1. Evaluation of susceptibility and acquired immunity to malaria.

2. Biology of novel protective proteins of Plasmodium.

3. Study of Plasmodium infected red cells under fluid force fields.

4. Metabonomics of the malarial parasite.

5. Nanolipid carrier mediated drug delivery in malaria.

6. Effect of mild and severe malaria in the brain of the vertebrate host.