Department of Chemical Sciences
School of Natural Sciences
  • Structure/Dynamics of Proteins and Fibrils from Solid State NMR

    Nuclear magnetic resonance spectroscopy of solid materials reveals structural and dynamics information. The methods make use of a combination of sample preparation, radiofrequency pulse sequence design, acquisition of multi-dimensional spectra techniques to get geometry information and structural elucidation…..

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  • Proteins and the Computational Microscope

    Theoretical modeling along with high performance computational simulations of biomolecules are probing how thermal motions of atoms drive diverse molecular scale processes such as charge transfer, enzymatic catalysis, biomolecular aggregation…..

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  • Rational Design of an Artificial Peroxidase

    We have rationally modified the active site of this thermostable P450 to introduce a residue at the distal heme pocket that could act as an acid-base catalyst and thus enhance the peroxidase activity in the mutant enzyme. This could potentially lead to the creation of a thermally stable artificial peroxidase...

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  • Spin Dynamics: Electron Spin Polarization and Relaxation

    Our research on Spin Dynamics attempts to understand mechanistic details that govern the generation electron spin systems in non-Boltzmann distribution and their evolution to Boltzmann distribution governed by the perturbing electron spin-lattice relaxation processes....

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  • Single-Molecule Protein Mechanics

    Single-molecule techniques are novel approaches to understand the structure-stability-function relationship of proteins, especially force spectroscopy methods in studying mechanically relevant proteins. These techniques are also useful to drive chemical reactions and bond-breakage at single-molecule/bond level to understand the reaction mechanism and get the elusive ‘transition state’ properties....

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About the Department

Scientists at the DCS explore the link between living systems and the physical laws that govern nature. They study molecules ranging in size as small as water and as large as a virus. The laws that govern interaction in molecules are best studied in well-defined and isolated small molecules. This information becomes applicable to design novel materials with exotic properties, of value to chemical and solar energy industries and to medical applications. To understand working of biological systems, studies are made on structure, dynamics and function of biological molecules. TIFR is a leader in state-of-the-art experimental techniques such as high field NMR, ultrafast lasers and single molecule methodologies.

News & events

  • Awards for Vivek Polshettiwar`s research group

    Mr. Rustam Singh received best poster award in 4th International Conference on Advanced Nanomaterial and Nanotechnology (ICANN-2015), one of the best nano-conference in India, organized by IIT, Guwahati during Dec 8-11, 2015.

    Mr. Rustam Singh received best poster award in ICONSAT 2016 organized by IISER, Pune and DST, Nanomission. He presented his recent work on, "TiO2 coated KCC-1 for photocatalysis: Nanoparticle formation and quantum confinement".

    Dr. Polshettiwar is recognized as one of the 'Emerging Investigators 2016' for Novel design strategies for new functional materials by Journal of Materials Chemistry A of Royal Society of Chemistry, UK.

    Dr. Polshettiwar has been awarded prestigious "Bronze Medal" by Chemical Research Society of India (CRSI) for 2017.

  • Awards for Jyotishman Dasgupta's Research Group


    Ms. Melby Johny (from Dr. Jyotishman Dasgupta's Research Group)




    Ms. Melby Johny got poster award for his poster titled "Tracking the photo-induced vesicle-to-fibril transition of H-Azo-Phe-Phe-OH in solution" in the 14th Optics Within Life Sciences (OWLS) meeting held in Mumbai during March 16th-19th 2016.






  • Awards for Deepa Khushalani`s Research Group

    TIFR research scholars  and staff have consistently garnered accolades at both international and national meetings. Congratulations on their latest achievements!

    Mr. Chandanshive Balasaheb B. (Research group of Prof. Deepa Khushalani)

    Mr. Chandansive Balasaheb B. won the 3rd spot in the best oral presentation award at  the International Conference On Nanomaterials and Nanotechnology (Nano 2015) held during Dec 7-10th at Trichengode,Tamil Nadu. The title of his talk was: "Hydroxyapaptite Nanotubes: Biocompatible and Internalization Study". Click here for pics! Read  more about research in the Khushalani lab here.


  • Awards for Ankona Datta`s research group

    Dr. Ankona Datta`s group has recently featured in the ACS Emerging Investigators in Bioinorganic Chemistry. Congratulations to Ankona and her group members! Read the full article here.

    Samsuzzoha Mondal, Ph.D. Scholar from Ankona Datta`s research group, won the RSC Best poster award at the 6th International Conference on Metals in Genetics, Chemical Biology, and Therapeutics held at I.I.Sc. Bangalore, February 17-20, 2016. Samsuzzoha`s poster was titled: "Sensing Signaling Phospholipids with ‘Turn on’ and Ratiometric Fluorescent Probes". Congrats Samsuzzoha!

    Anindita Sarkar, Ph.D. Scholar from Ankona Datta`s research group, won the best poster award in the international conference on Optics Within Life Sciences (OWLS-2016) held at TIFR during March 16-19. Anindita`s poster was titled: 'Turn-on' Fluorescence Sensors for Imaging Mn(II) in Live Cells'. Congrats Anindita!

    Ankona`s research group works in the areas of Chemical Biology and Synthetic Chemistry, Molecular Biophysics and Imaging, and Bioinorganic and Biomimetic Chemistry within the department. Click here to learn more about Ankona`s research program.