School of Natural Sciences
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Deciphering the Catalytic Activity of an Orphan P450 enzyme
A systematically screened several fatty acids (saturated and monounsaturated) for their potential as substrates for CYP175A1 shows that the wild type enzyme could catalyze the reaction of mono-unsaturated fatty acids but not of saturated fatty acids...
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Spin Dynamics: Electron Spin Polarization and Relaxation
Our research on Spin Dynamics attempts to understand mechanistic details that govern the generation electron spin systems in non-Boltzmann distribution and their evolution to Boltzmann distribution governed by the perturbing electron spin-lattice relaxation processes....
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Single-Molecule Protein Mechanics
Single-molecule techniques are novel approaches to understand the structure-stability-function relationship of proteins, especially force spectroscopy methods in studying mechanically relevant proteins. These techniques are also useful to drive chemical reactions and bond-breakage at single-molecule/bond level to understand the reaction mechanism and get the elusive ‘transition state’ properties....
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Rational Design of an Artificial Peroxidase
We have rationally modified the active site of this thermostable P450 to introduce a residue at the distal heme pocket that could act as an acid-base catalyst and thus enhance the peroxidase activity in the mutant enzyme. This could potentially lead to the creation of a thermally stable artificial peroxidase...
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Title : To be announced
Abstract :
About the Department
Scientists at the DCS explore the link between living systems and the physical laws that govern nature. They study molecules ranging in size as small as water and as large as a virus. The laws that govern interaction in molecules are best studied in well-defined and isolated small molecules. This information becomes applicable to design novel materials with exotic properties, of value to chemical and solar energy industries and to medical applications. To understand working of biological systems, studies are made on structure, dynamics and function of biological molecules. TIFR is a leader in state-of-the-art experimental techniques such as high field NMR, ultrafast lasers and single molecule methodologies.
News & events
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Prof. R.V. Hosur awarded "Padmashree"
One of our colleagues, Prof. R.V. Hosur has been awarded "Padmashree" by the Government of India. Prof. Hosur is currently the Senior Professor in the Department. He is also been holding the position of the Director at the Centre for Excellence in Basic Sciences at Kalina, Mumbai
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Awards for DCS Graduate Students
TIFR research scholars have consistently garnered accolades at both international and national meetings. Congratulations on their latest achievements!
Ms Aditi Bhatacherjee (Research group of Prof. Sanjay Wategaonkar)
- Ms Aditi Bhattacherjee received one of the Best Poster awards at the "Trombay Symposium on Radiation and Photochemistry" held at BARC in January 2014.
- She had also received the Poster award earlier at the "International Conference on Horizons in Hydrogen Bond Research" held in Antwerp, Belgium in September 2013.
Mr. K. Hemachandra (Research group of Dr. A.S.R. Koti)
- Mr. K. Hemachandra, recieved the "Student Research Achievement Award" for the best poster in Mechanobiology section in the 58th Biophysical Society Meeting held at San Francisco, California, USA, held during February 15-19, 2014.
Mr. Biswajit Mishra & Ms. Shama Parween (Research group of Prof. Deepa Khushalani)
- Mr. Biswajit Mishra and Ms. Shama Parween received the Best Poster Award at International Union of Materials Research Societies International Conference in Asia (IUMRS-ICA) held at Bangalore for their poster entitled "ZnTiO3: Synthesis, Characterization and Exclusive Visible Light Photocatalysis".
Mr. Amitava Acharjya (Research group of Dr. Vivek Polshettiwar)
- Mr. Amitava Acharjya, recieved the Best Poster Award at 6th International Conference On Nano Science And Technology (ICONSAT) 2014 held at Chandigarh during March 3-5, 2014 for his poster entitled "Shape Controlled Synthesis of Nano Cobalt Oxide for Catalytic Applications"
Mr. Bappaditya Chandra (Research group of Prof. Sudipta Maiti)
- Mr. Bappaditya Chandra won the best oral presentation award at the National Magnetic Resonance Society Symposium[NMRS-2014] held at Tezpur University, Tezpur, between Feb 2- 5, 2014. His research presentation on the project conducted in collaboration with Prof. P. K. Madhu was titled: "Combining fluorescence and slow NMR technique to determine the atomic level structure of transient toxic amyloid beta oligomers".
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Prof. S. Mazumdar elected as Fellow of NASI
One of our colleagues, Prof. Shyamalava Mazumdar, has been elected as Fellow of the National Academy of Sciences India
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Technological innovation from Maiti group
Prof. Sudipta Maiti`s research group has made significant contributions to the development of biophotonic instrumentation and methodology.
Calendar
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May 27, 2014 at 2.30 pm in AG-69
Seminar by Mr. Rahul Gera, Dept. of Chemical Sciences, TIFR
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May 26, 2014 at 4.00 pm in AG-69
Seminar by Mr. Debanjan Bhowmik, Dept. of Chemical Sciences, TIFR, Mumbai
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May 12, 2014 at 4.00 pm in AG-69
Seminar by Dr.Virabhadrarao Kaliginedi, University of Bern, Switzerland
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April 28, 2014 at 4.00 pm in AG-69
Seminar by Dr. Ranja Sarkar, Dept. of Chemical Sciences, TIFR