School of Natural Sciences
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Spin Dynamics: Electron Spin Polarization and Relaxation
Our research on Spin Dynamics attempts to understand mechanistic details that govern the generation electron spin systems in non-Boltzmann distribution and their evolution to Boltzmann distribution governed by the perturbing electron spin-lattice relaxation processes....
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Deciphering the Catalytic Activity of an Orphan P450 enzyme
A systematically screened several fatty acids (saturated and monounsaturated) for their potential as substrates for CYP175A1 shows that the wild type enzyme could catalyze the reaction of mono-unsaturated fatty acids but not of saturated fatty acids...
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Chemistry driven by delocalized molecular motions
Chemical reactions are often conceptualized by making and breaking one bond at a time. The idea of localized bond alterations inhibits intuitive thinking about the structure as a whole. The Dasgupta group is focusing on creating a theme using collective motions existing in the molecular structure to drive selective and efficient chemistry...
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Imaging Protein Dynamics at Work
Molecular fluorescence, when observed with a time resolution of a few picoseconds, becomes a powerful tool for revealing the ‘wiggling and jiggling’ which makes the biological world ‘living’. With the state-of-the-art laser technology available today one can observe dynamics of molecules in ultrafast timescales with high sensitivity and selectivity. …..
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Single-Molecule Protein Mechanics
Single-molecule techniques are novel approaches to understand the structure-stability-function relationship of proteins, especially force spectroscopy methods in studying mechanically relevant proteins. These techniques are also useful to drive chemical reactions and bond-breakage at single-molecule/bond level to understand the reaction mechanism and get the elusive ‘transition state’ properties....
About the Department
Scientists at the DCS explore the link between living systems and the physical laws that govern nature. They study molecules ranging in size as small as water and as large as a virus. The laws that govern interaction in molecules are best studied in well-defined and isolated small molecules. This information becomes applicable to design novel materials with exotic properties, of value to chemical and solar energy industries and to medical applications. To understand working of biological systems, studies are made on structure, dynamics and function of biological molecules. TIFR is a leader in state-of-the-art experimental techniques such as high field NMR, ultrafast lasers and single molecule methodologies.
News & events
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Prof. R.V. Hosur awarded "Padmashree"
One of our colleagues, Prof. R.V. Hosur has been awarded "Padmashree" by the Government of India. Prof. Hosur is currently the Senior Professor in the Department. He is also been holding the position of the Director at the Centre for Excellence in Basic Sciences at Kalina, Mumbai
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Student Research Achievement Award for Mr. K. Hemachandra
Mr. K. Hemachandra, one of the research scholars in our Department, received the "Student Research Achievement Award" for the best poster in mechanobiology section in the 58th Biophysical society meeting held at San Francisco, California, U.S.A held during February 15-19, 2014.
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Best Poster Awards for Ms. Aditi Bhattacherjee
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Ms Aditi Bhattacherjee received one of the Best Poster awards at the "Trombay Symposium on Radiation and Photochemistry" held at BARC in January 2014.
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She had also received the Poster award earlier at the "International Conference on Horizons in Hydrogen Bond Research" held in Antwerp, Belgium in September 2013.
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Prof. S. Mazumdar elected as Fellow of NASI
One of our colleagues, Prof. Shyamalava Mazumdar, has been elected as Fellow of the National Academy of Sciences India
Calendar
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March 31, 2014 at 4.00 pm in AG-69
Seminar by Dr. Amit Jaiswal, Indian Institute of Technology, Guwahati
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March 24, 2014 at 4.00 pm in AG-69
Seminar by Ms. Anindita Sarkar, Dept. of Chemical Sciences, TIFR, Mumbai
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March 20, 2014 at 2.30 pm in AG-80
Ph.D. Synopsis Seminar by Ms. Pushpa Mishra
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March 10, 2014 at 4.00 pm in AG-69
Seminar by Mr. Dwaipayan Dutta Gupta