Curriculum Vitae

 

Name :                                    Ramakrishna V. Hosur

 

Date of  Birth:                        16. 05. 1953

 

Marital status:                       married and have two children

 

Address:                                 Department of Chemical Sciences

                                                Tata Institute of Fundamental Research

                                                Homi Bhabha Road, Mumbai 400 005

                                                Tel:  2278 2488 (office), 2280 4635 (Residence)

                                                Fax: 2280 4610

                                                e-mail : hosur@tifr.res.in

 

                                                Director

                                                UM-DAE Centre for Excellence in Basic Sciences

                                                University of Mumbai, Kalina campus

                                                Mumbai-400098

                                                Email:director@cbs.ac.in

 

 

Education:

 

S. No.

Degree

Subject

Class/ marks

Year

University

Remarks

1.

B. Sc

Chemistry, Physics, maths

 First, 73%

1971

Karnataka

5th rank

2.

M. Sc

Chemistry

First, 73.7%

1973

IIT - Mumbai

3rd rank

3.

Ph. D.

Chemistry

 

1978

TIFR, Mumbai

 

4.

Post-doc*

Protein NMR

 

1981-83

ETH-Zurich, Switzerland

 

*In the Group of Prof.  K. Wuthrich (Institute of Biophysics and Molecular Biology) and in collaboration with Prof. R. R. Ernst (Institute of Physical Chemistry) both at ETH.  Prof. Ernst won the Nobel prize for Chemistry in 1991 and Prof. Wuthrich won the Nobel prize for Chemistry in 2002.

 

Academic Positions held:

 

S. No.

Period

Place of Employment

Designation

1.

Aug 78 – July 80

TIFR

Research Associate

2.

Aug 80 – Jan 86

TIFR

Fellow

3.

Feb 86 – July 91

TIFR

Reader

4.

Aug 91 – July 96

TIFR

Associate Professor

5.

Aug 96 – July 99

TIFR

Professor (G)

6.

Aug 99 – July 2003

TIFR

Professor (H)

7.

Aug 2003 – till date

TIFR

Senior professor (I)

 

Spent three months on a sabbatical leave from TIFR during August 20 -  November 20, 1988 at Columbia University, New york in the laboratory of Prof. D. J. Patel

 

Administrative responsibilities at TIFR:

 

1. Chairperson, Department of Chemical Sciences, TIFR, April 1, 2000- March 31, 2006

2. Chairperson, Advisory Committee for Administration and Finance (ACAF), TIFR,        June 2, 2003- March 31, 2005

3. Chairperson, Standing Committee on Administration (SCA), TIFR, April 1, 2005 – till date

4. Member, Management Board of Homi Bhabha Centre for Science Education (HBCSE), TIFR, April 1, 2004- March 31, 2006

5. Chief Vigilance Officer (CVO) of TIFR, April 2002- March 2004

           

 

Convener for the National Facility for High Field NMR at TIFR, Mumbai (2002-till date)

 

I have played a major role in the establishment, running and the academic activities of the National Facility for High Field NMR, at TIFR. The Facility was established in 1983, with the support from Department of Science and Technology, Govt. of India and TIFR, and then it had the High Resolution 500 MHz NMR spectrometer, the only one of its kind in the country. It served immensely, the needs of the scientific community in the country. Keeping in tune with the growing demands and the technological developments, the facilities have been regularly upgraded at the Facility. In 1995, a 600 MHz NMR spectrometer was added, an 800 MHz spectrometer was added in 2006 and in 2009 a 700 MHz machine has been installed. Currently, I am the convener of this Facility. The Facility has played a major role in training the NMR community of this country in theory, practice and use of the NMR technique, by organizing regular workshops and conferences.

 

Research Interests

 

My major area of research is at the Chemistry-Biology interface, and in particular, nuclear magnetic resonance and its application to structure, dynamics and interaction of biological macromolecules. In the past I have worked on lipids and membrane organization, DNA duplexes, triplexes and their specific interaction with proteins. My present research covers development of NMR pulse sequences, development of software algorithms for NMR data analysis, protein-DNA recognition, structure and dynamics of DNA quadruplexes, protein folding, structure and dynamics of proteins and their complexes with specific substrates/inhibitors. A variety of protein and nucleic acid systems produced synthetically and/ or by gene expression methods are being investigated.

 

Areas of Specialization: Molecular Biophysics, Structural Biology, Biomolecular NMR, Biophysical Chemistry

 

Publications:

Articles :                      203 (journals:165, book articles:9, conference proceedings:27, popular: 2)

Books :                        3 (1 written and 2 edited)

Book reviews:             3

Technical reports:        3

 

Ph. D students supervised

            Name                           Year                Present Position

-----------------------------------------------------------------------------------------------------

1.         Dr. M. Ravikumar       1987                Michigan University, USA

2.         Dr. A. Sheth                1988                with Wiley-Eastern

3.         Dr. A. Majumdar        1990                John Hopkins, Baltimore, USA

4.         Dr. R. Ajaykumar       1992                IBM, USA

5.         Dr. R. Nibedita           1993                USA                           

6.         Dr. A. Madan              1995                University of Washington, Seatle

7.         Dr. Mrs. S. Singh        1996                NIH, Bethesda, USA

8.         Dr. P.K. Radha           1997                Boston, USA

9.         Dr. P. K. Patel             1999                Massachusetts

10.       Dr. Sarata Sahu           2000                Carnegie-Melon University, USA

11.       Dr. P. Khandelwal      2000                Bristol Meyers, USA

12.       Dr. S. C. Panchal        2001                Abbot Laboratories, USA                  

13.       Dr. N. S. Bhavesh       2003                Faculty at ICGEB, New Delhi

14.       Dr. A. Chatterjee        2006                SCRIPPS, California, USA

15.       Dr. Ashutosh Kumar   2007                Faculty at IIT, Mumbai

16.       Dr. Jeetender Chugh   2008                Michigan, USA

17.       Dr. P. M. K. Mohan    2009                UTMB, Texas, USA

18.       Mr. Manoj Rout          2011

19.       Mr. Dinesh Kumar      2011                CBMR, Lucknow

20.       Ms. Swagata Chakraborty (working)

21.       Mr. Jitender Reddy (working)

22.       Ms. Pushpa Mishra (working)

 

Dr. M. Ravi Kumar, Dr. Ananya Majumdar, Dr. Sarata Sahu and Dr. Neel S. Bhavesh won the ‘Best Ph. D. thesis Award’ of TIFR. Dr. M. Ravi Kumar won the Bruker young scientist award. Dr. Neel S. Bhavesh got the ‘honorary mention’ from the International Union of Pure and Applied Chemistry (IUPAC) for his thesis work. He also got the Platinum Jubilee Young Scientists Award-2009 of National Academy of Sciences, Allahabad and Young Associate of the Indian Academy of sciences, Bangalore. Dr. P. M. K. Mohan won the Young Scientist award of the Indian Science Congress Association (ISCA). Many of the students have won ‘best oral presentation’ and ‘best poster presentation’ awards during the national conferences.

 

M. Sc students

1.         Mr. Subhradeep Paul, 2011   

2.         Mr. Venus Singh Mithu (working)

3.         Mr. Supriya Pratihar (working)

 

Post Doctoral Fellows

            Dr. Amarendra Tunga

            Dr. Subhendu Seth

            Dr. Ragini Sinha (2001-2002)

            Dr. Maneesha Barve (2004- till March 2007)

            Dr. Shilpy Sharma (Aug 2006- September 11, 2008)

            Dr. Kalyana Venneti (November 2011 -

 

Summer students

 

            I have been taking one student every summer under the VSRP (Visiting Students Research Programme) scheme of TIFR. I have also taken students from the Indian Academy of Sciences under their Summer Fellowship programme. Many students from different universities (D.Y. Patil university, Mumbai, Pune University, Lucknow University) have done their M.Tech / M Phil- projects under my supervision.

 

Teaching activities

  1. Taught regularly graduate course on ‘Magnetic Resonance’ to Ph. D. students (30-40 lectures each time) at TIFR
  2. Taught several times graduate course on mathematics to Ph. D students at TIFR (40 lectures)
  3. Gave lectures at many summer schools and workshops on NMR across the country (5-6 lectures each time).
  4. Gave lectures at many UGC refresher courses organized for the benefit of College teachers.
  5. taught course of 10-15 lectures on NMR and its applications at IIT- Mumbai and IIT- Roorkee
  6. lectured at many continuing education programmes at IIT- Mumbai
  7. participated as member of the committee of International Chemistry Olympiad, held in India in 2001

 

Awards and Academy Fellowships

 

(a)        Awards

 

            ‘Honorary Mention’ for excellent lecture notes in the two months long International Summer School on Quantum Chemistry held at Uppsala, Sweden and Norway, in Aug-Sept, 1975.

           

 

Young scientist award

Bruker NMR Company

1983

 

Young Scientist Medal

Indian National Science Academy

1984

 

B. D. Tilak Lecture

Bombay University

1989

 

B. M. Birla award

Birla Science Centre

  1992

 

R. K. Asundi Lecture

Indian National Science Academy

  1998

 

3rd annual award

Society for cancer research

1998

 

Dr. Jagdish Shankar Lecture

Indian National Science Academy

2003

 

IICB Foundation day lecture

IICB, Kolkata

2004

 

RRL Foundation day lecture

RRL, Trivandrum

2006

 

JC Bose National Fellowship

DST, Govt of India

2007

 

Prof. GN Ramachandran Gold medal

CSIR

2009

 

Fr. Yeddanapalli Memorial lecture

Indian Chemical Society

2009

 

 

(b) Academy Associate /  fellowships

 

Young Associate, Indian Academy of Sciences                                           1985-88

Fellow, Indian Academy of Sciences (F. A. Sc.)                                          1994

Fellow,  Indian National Sceince Academy (F. N. A)                                  1995

Fellow, National Academy of Sciences (F. N. A. Sc)                                   1997

Fellow, TWAS, The Academy of Sciences for the Developing World         2008

 

Honours and Distinctions

 

(a)        President / Council member

 

            President, Indian Biophysical Society, 2003-05

            President, New Biology Section, Indian Science Congress, 2005

            President, National Magnetic Resonance Society (NMRS), 2009-

            Council, Chemical Research Society of India, 2002-04

            Council, ICMRBS, 2005-2014

            Council, Centre for Biomedical Magnetic Resonance, 2006-

            Council, Research Council of IICB, Kolkata, 2007-

            Chair, INSA National Committee of IUPAB, 2008-11

            Council, INSA, 2008-10

            Council, NASI, 2009-11

            Council, ISCA, 2005-

            Chairman, Ad-hoc Board of Studies- Biophysics, Mumbai University, 2011-14

            Academic Council, University of Mumbai, June 2011-

            Board of University Teaching and Research (BUTR), Mumbai University, 2011-

            International Union of Pure & Applied Biophysics, General Assembly, 2011

 

(b)        Memberships of selection Committees

 

1.         Member, selection and promotion committee for academic staff at IIT- Mumbai and IIT-Madras, IIT-Roorkee

2.         Member, selection committee for Readers and Professors at Panjab  University, Chandigarh

3.         Member, selection committee for Associate Professors and Professors at All India Institute of Medical Sciences, New Delhi

4.         Member of selection committee for BRUKER Young Scientist Award      

5.         Member, Selection Committee of JN Tata Endowment for support for higher education abroad.

6.         Expert, Committee of Narotam Sakhsaria Foundation for support for higher education abroad

7.         Member, selection committee for S. S. Bhatnagar prize in Chemistry, 2005, 2007

8.         Member, selection committee for Readers in Biophysics, Maharashtra Public Service Commission (MPSC), 2008

9.         Member, selection committee for Professors of Biophysics at NIMHANS, Bangalore, 2008

10.       Member, Chemistry Sectional Committee, Indian Academy of Sciences, 2004-06

11.       Member, Chemistry Sectional Committee, INSA, 1998-2001

12.       Member, Membership Scrutiny Committee of NASI, 2009-

13.       Member, Fellowship Scrutiny Committee of NASI, 2009-

14.       Member, INSA Sectional Committee for Biochemistry, Biophysics, 2007

15.       Member, INSA Sectional Committee for Multidisciplinary Subjects, 2007

16.       Member of the Jury for Aditya Birla Scholarships.

17.       Research and Recognition Committee (RRC) of Biophysics, Mumbai University, 2011-

 

 

(c)        Memberships of Scientific Societies

           

            Founder Member and Life Member National Magnetic Resonance Society

Member, International Society of Magnetic Resonance

            Member, Society for Cancer Research and Communication, Mumbai

            Life member, Indian Biophysical Society.

            Life member, Indian Science Congress Association

            Life member, Society for Biological Chemists, India

            Life member, Chemical Research Society of India

            Member, American Chemical Society, 2008-

 

 (d)       Editorial Boards         

 

1.         Current Science (1994-97)

2.         Indian Journal of Biochemistry and Biophysics (1999 – till date)

3.         Guest Editor, PINSA-A, July issue 2004

 

(e)        Reviewer for International Journals

           

      International Journal of Quantum Chemistry

      Journal of Biomolecular NMR

      Biochemistry USA

      Biochim. Biophys. Acta

      FEBS Lett

      Nucleic Acids Research

      Critical Reviews of Biochemistry and Molecular Biology

      Magnetic Resonance in Chemistry

Journal of Molecular Structure

Biophysical Journal

J. Phys. Chem. USA

J. Biomol. Struct. Dyn. USA

Lett. Drug. Design and Discovery

Protein Science

            Nature-Communications

            Journal of Magnetic Resonance

 

(f)         Reviewer for grant proposals submitted to funding agencies

 

            International

 

            Wellcome Trust, UK

            SWISS Government, Erwin Schrodinger Fellowship

            INDO-SWISS collaborative projects

            INDO-FRENCH collaborative projects

            Human Frontier Science Program (HFSP) proposals

            Research Award Program, City University of New York

            Austrian Science Foundation

           

            National

-

            Department of Science and Technology (DST, Govt of India)

            Department of Biotechnolgy (DBT, Govt of India)

            Council of Scientific and Industrial Research (CSIR, Govt of India)

            Board of Research in Nuclear Sciences (BRNS)

            DS Kothari Post Doctoral Fellowship of UGC

 

(g)        Examiner of Ph. D. Theses

 

            Indian Institute of Science, Bangalore

            Indian Institute of Technology, Mumbai

            Indian Institute of Technology, Delhi

            University of Hyderabad

            IICB, Kolkata

            IIT, Roorkee

            IICT (JNTU) Hyderabad

            Osmania University, Hyderabad

            Madras University, Chennai

            Mumbai University, Mumbai

 

 

(h)       Other Distinctions      

 

 

Secretary

National Magnetic Resonance Society (NMRS)

1994-1997

 

Vice president

National Magnetic Resonance Society (NMRS)

2006-2008

 

Member, DBT Task Force on Basic Research

Department of Biotechnology, Govt. of India

1994-97

 

Member, DST committee for Young Scientists

Department of Science and technology, Govt of India

 

 

Member, Expert Committee of CSIR

CSIR, New Delhi, Govt of India

 

 

Honorary Professor

Centre for Biomedical Magnetic Resonance, Lucknow

2006

 

Member, Management Committee of SIF, Bangalore

Sophisticated Instruments Facility, Bangalore

1991-94, 2000-

 

Member, MAC, National Facility for High Field NMR

National Facility for High Field NMR at TIFR, Mumbai

 

 

Member, PAC, National Facility for High Field NMR

National Facility for High Field NMR at TIFR, Mumbai

 

 

Secretary

Indian Biophysical Society

2001 -2003

 

Convenor

Indian National Science Academy, Mumbai Chapter

1997-2000

 

Secretary

National Committee of IUPAC, INSA

1994-1997

 

Alternate member

Council of International Conference on Magnetic Resonance in Biological Systems (ICMRBS)

1984-1994

 

Member, IUPAB Subcommission on cellular and macromolecular Biophysics

International Union of Pure and Applied Biophysics (IUPAB)

1996

 

 

Member, DBT task force on Infra structure and centers of excellence

Department of Biotechnology, Govt. Of India

2002-2005

 

 

Member, Adhoc Board of Studies in Biophysics

Mumbai University

2002-

 

 

 

Member, Advisory board, Biotechnology

Mumbai University

2003-

 

 

Member, Expert committee of RRL, Jorhat

Council of scientific and industrial research

2004-

 

 

Member, PAC on life sciences of SERC, DST

Department of Science and Technology

2004-07

 

 

Member, Advisory Board, Prof. Rangadhama Rao Memorial Lecture

Indian National Science Academy

2008

 

 

 

Visits abroad under Exchange Programmes of INSA

 

                        INDO - UK Exchange Programme                            1990

                        INDO - Netherlands  Exchange Programme              1996

Leader of Indian Delegation to IUPAB congress, Beijing, October 30-November 3, 2011

 

Invited Lectures at International Conferences

 

1.         International Conference on Theoretical Biochemistry  and  Biophysics, Goa, India                                                                                                           1980

2.         International Conference on Magnetic Resonance in Biological systems (ICMRBS) at

 

                                    Goa, India                                                                   1984

                                    Todtmoos, Germany                                                   1986

                                    Madison, USA (Plenary Speaker)                               1988

                                    Leicester, UK                                                              1990

                                    Jerusalem, Israel                                                          1992

                                    Veldhoven, The Netherlands                                      1994

                                    Florence, Italy                                                             2000

                                    Hyderabad, India (Plenary Speaker)                          2005

                                    Gottingen, Germany                                                   2006

                                    Cairns, Australia                                                         2010

 

3.         International Conference on Trends in Biotechnology

                                    at Kualalumpur, Malaysia                                           1990

 

4.         Workshop on Determination of Three Dimensional

            Structures of Proteins and Nucleic Acids in solution.

                                    at Ascona, Switzerland.                                              1990

 

5.         Congress Ampere on Magnetic Resonance and

                                    Related Phenomena, Rome, Italy                               1986

 

6.         International Biophysics Congress, Amsterdam                                 1996

 

7.         International Symposium on Structure, dynamics

and folding in proteins as viewed from Pressure Axis

Otsu, Japan. January 25-27, 2001                                                       2001

 

8.                  International Symposium of the Protein Society on

‘Protein Structure and Function’ held at  IIT Bombay,

October 18-20, 2002                                                                           2002

 

9.         International Symposium on Structural Biology and

Functional Genomics, held at National university of Singapore,

December 2-4, 2002                                                                            2002

 

10.       Special Symposium on ‘New Developments in NMR Methodology’

held at IISc, Bangalore, February 3-4, 2003                                      2003

 

11.              International seminar on ‘Frontiers in Basic and Applied

Molecular Biology’held at University of Calcutta,

January 9-12, 2003                                                                              2003   

 

12.       International conference on Chemistry Biology Interface: Synergistic New             frontiers, November 22-27, 2004, New Delhi                                 2004   

 

13.       International Symposium on Emerging Trends on Genomic and Proteomic Sciences, October 15-18, Mumbai (Plenary Speaker).                   2006

 

14.       INSA-CAS symposium on Structural Biology, December 21-23,

            Bangalore                                                                                            2007

 

15.       International Workshop on Physics-Biology Synergy,

            December 12-14, Hyderabad                                                              2007

 

16.       International Centenary Symposium on Future Directions in

            NMR, October 19-22, IISc, Bangalore                                              2008

 

17.       International Conference on Emerging Trends in Biological

            Sciences, KIIT, Bhubaneshwar, Oct 24-25 (keynote speaker)           2008

 

18.       International Symposium on Emerging Areas in Bioscience

            and Bioengineering, IIT-Mumbai, Feb 27-28                                     2009

 

 

 

19.       Asian Biophysics Association Symposium, Jan 11-15, 2009

            Hong Kong (Plenary Speaker)                                                            2009

 

20.       International Symposium on Emerging Areas in Bioscience

            and Bioengineering, IIT-Mumbai, Feb 27-28                                     2009

 

21.       INDO-US symposium and workshop on macromolecular structures,

            IIT-Bombay, Feb 21-24, 2011                                                            2011

 

Chaired sessions at International Conferences

 

          International Biophysics Congress, New Delhi                                  1999

           

            ICMRBS, Jerusalem, Israel                                                                1992

 

            NMR in Molecular Biology,  Strassbourg, France                              2003

 

            ICMRBS, Hyderabad                                                                         2005

 

            Asian Biophysics Association Symposium, New Delhi                     2011

           

International symposium on Pure and Applied Chemistry,

            Mumbai, (inaugural session)                                                               2011

 

            17th International Biophysics Congress, Beijing                                 2011

 

Delivered plenary lectures, invited lectures, inaugural lectures, and chaired sessions at many National Conferences relating to NMR and Biochemistry and Biophysics. Delivered lectures at UGC workshops and Refresher Courses and DST INSPIRE Camps.

         

International Conferences Organised

 

(1)        Convenor of the International Symposium on Recent Trends in Biomedical Research, at TIFR, Mumbai during September 27-29, 1999.

 

(2)        Convenor, International Symposium on Magnetic Resonance and Biomolecular Structure and Function, at TIFR, Jan 17-20, 2000

 

(3)        Chairman, local organizing committee, International Symposium on Advances in Bioinorganic Chemistry, at TIFR, November 19-24, 2000

 

(4)               Member, Organising Committee of International Conference of Magnetic Resonance in Biological Systems held at Hyderabad, India, during January 16-21, 2005

 

(5)        Member, National Advisory Committee on International Workshop on Recent trends in Solid State NMR in Biological systems, Bangalore, January 24-26, 2005

 

(6)        Member, National Advisory Committee on International Workshop on Recent       Trends in Biomedical NMR, New Delhi, January 12-14, 2005

 

(7)        Chairman, local organizing committee, International Symposium on Advances in Bioinorganic Chemistry, and Asian Bioinorganic Chemistry Conference at Goa, December 5-10, 2004

 

(8)        Member, National Advisory Committee, International Centenary Symposium on Future Directions in NMR, October 19-22, 2008, IISc, Bangalore           

 

(9)        Chairman, local organizing committee, International Symposium on Advances in Bioinorganic Chemistry, and Asian Bioinorganic Chemistry Conference at Mumbai, November 2-7, 2009

 

(10)      Member, National advisory Committee of INDO-SWISS workshop on NMR, 2011-12

 

National Conferences Organized

 

(1)        ‘NMR and Health Care’ as part of the Indian Science Congress, 2005

(2)        Member, National Advisory Committee of NMR Conference to be held at Bangalore, February 5-8, 2012