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Publications: Shyamalava Mazumdar

2011

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Interaction of gammaxene with site specific mutants of Cytochrome P450cam
Saptaswa Sen, Soumen Kanti Manna & Shyamalava Mazumdar
Ind. J. Chem. Sec. A, (2011), 0000

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Structural Design of the Active Site for Covalent Attachment of the Heme tothe Protein Matrix: Studies on a Thermostable Cytochrome P450
Sandeep Goyal, Megha S. Deshpande, and Shyamalava Mazumdar
Biochemistry
(2011), 50, 1042–1052


2010

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Non-covalent dimers of the lysine containing protonated peptide ions in gaseous state: electrospray ionizationmass spectrometric study
Shibdas Banerjee and Shyamalava Mazumdar
J. Mass Spectrom (2010), 45, 1212–1219

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Modification of the heme active site to increase the peroxidase activity of thermophilic cytochrome P450: A rational approach
R. K. Behera, S. Goyal and Shyamalava Mazumdar
J. Inorg. Biochem (2010),  104 1185–1194

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Covalent linkage of CYP101 with the electrode enhances the electro-catalytic activity of the enzyme: Vectorial electron transport from the electrode
S. D. Mhaske, M. Ray and Shyamalava Mazumdar
Inorganica Chimica Acta (2010), 363, 2804–2811

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Direct Electrochemistry of Dinuclear CuA fragment from cytochrome c oxidase of T. thermophilus at surfactant modified glassy carbon electrode
J. Rajbongshi, D K Das, S. Mazumdar
Electrochim. Acta (2010), 55, 4174–4179

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Tuning the substrate specificity by engineering the active site of cytochrome P450cam: A rational approach
Soumen Kanti Manna and S. Mazumdar
Dalton Trans., (2010),  39, 3115–3123

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Thermodynamic basis of the thermostability of CYP175A1 from Thermus thermophilus
Rabindra Kumar Behera and S. Mazumdar
Int J Biol Macromol (2010), 46, 412–418

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Effects of salts on the charge-state distribution and the structural basis of the most intense charge-state of the gaseous protein ions produced by electrospray ionization
H. Prakash, B.T. Kansara and S. Mazumdar
Int J Mass Spectrom (2010), 289, 84–91


2009

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Succinylation of cytochrome c investigated by electrospray ionisation mass spectrometry: Reactive lysine residues
Halan Prakash and S. Mazumdar 
Int J Mass Spectrom (2009), 281, 55-62

2008

- - Engineering of Thermus thermophilus Cytochrome c552: Thermally Tolerant Artificial Peroxidase
Hiroshi Nakajima, Yusuke Ichikawa, Yuh Satake, Nobuyuki Takatani, Soumen Kanti Manna, Jitumani Rajbongshi, Shyamalava Mazumdar, Yoshihito Watanabe
ChemBioChem
(2008),  9(18),  2954-2957
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Roles of two surface residues near the access channel in the substrate recognition by cytochrome P450cam

Rabindra Kumar Behera and Shyamalava Mazumdar

Biophys. Chem (2008),  135,  16

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Inhibition of Bacterial Oxidases by Formamide and analogues

Sayan Gupta and Shyamalava Mazumdar

Biol. Chem., (2008), 389(5), 599-607

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Reversible inactivation of cytochrome P450 by alkaline earth metal ions: Auxiliary metal ion induced conformation change and formation of inactive P420 species in CYP101

Soumen K. Manna, Shyamalava Mazumdar

J. Inorg. Biochem. (2008),  5-6, 1312-1321

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Effect of Polar Solvents on the Optical Properties of Water-dispersible Thiol-Capped Cobalt Nanoparticles

Nusrat J M Sanghamitra and Shyamalava Mazumdar

Langmuir (2008),  24 (7), 3439-3445

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Conformational dynamics coupled to protonation equilibrium at the CuA site of T. thermophilus: Insights into the origin of thermostability

Nusrat J.M. Sanghamitra and Shyamalava Mazumdar

Biochemistry (2008) 47, 1309 - 1318

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Protein encapsulation into mesoporous silica hosts

Y. S. Chaudhary, S. K. Manna, Shyamalava Mazumdar, D Khushalani

Micropor. Mesopor. Mater. (2008), 109 (1-3), 535-541

2007

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Thermostability of proteins: Role metal binding and pH on the stability of the dinuclear CuA site of Thermus thermophilus

A. Sujak, Nusrat J. M. Sanghamitra, O. Maneg, B. Ludwig and Shyamalava Mazumdar

Biophys. J. (2007) 93(8), 28452851

2006

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Effect of Alcohols on Binding of Camphor to Cytochrome P450cam: Spectroscopic and Stopped Flow Transient Kinetic Studies

R. Murugan and Shyamalava Mazumdar

Arch. Biochem. Biophys. (2006) 455(2), 154-162

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Role of Threonine 101 on the stability of the heme active site of cytochrome P450cam: Multi-wavelength Circular Dichroism Studies

Soumen Kanti Manna and Shyamalava Mazumdar

Biochemistry (2006), 45(42), 12715 - 12722


2005

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Structure of the heme centre and its redox properties in the C357M mutant of cytochrome P450cam

R. Murugan and S. Mazumdar

ChemBioChem, (2005) 6, 1204-1211

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Direct Correlation of the Crystal Structure of Proteins with the Maximum Positive and Negative Charge-States of Gaseous Protein Ions Produced by Electrospray Ionization

Halan Prakash and S. Mazumdar

J. Am. Soc. Mass Spectrom. (2005), 16, 1409-1421

2004

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Role of substrate on the conformational stability of the heme active site of cytochrome P450cam: effect of temperature and low concentrations of denaturants

R. Murugan and S. Mazumdar

J. Biol. Inorg. Chem. (2004), 9, 477-488

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A simple formalism on dynamics of proteins on potential energy landscapes

R. Murugan and S. Mazumdar

Protein Science, (2004), 13, 487-493

2003

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Stabilization of partially folded states of cytochrome c in aqueous surfactant: effects of ionic and hydrophobic interactions

K. Chattopadhyay and S. Mazumdar

Biochemistry (2003) , 42, 14606 - 14613

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Effect of redox potential of the heme on the peroxidase activity of cytochrome b562

S.  Mazumdar , S. L. Springs , G. L. McLendon

Biophys. Chem., (2003), 105, 263268

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An NMR and circular dichroism study of the interaction of thiocyanate with human and cross-linked hemoglobin: identification of Lys-a-99 as a possible dissociation linked binding site

A. K. Sau, D. Currell , S.  Mazumdar , S. Mitra

Biophys. Chem., (2003) ,106, 233240

2002

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Interaction of sodium dodecyl sulfate with human native and cross-linked hemoglobins: A transient kinetic study

A. K. Sau, D. Currell, S.  Mazumdar and S. Mitra

Biophys. Chem., (2002), 98, 267-273.

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NMR studies on interaction of lauryl maltoside with cytochrome c oxidase: A model for surfactant interaction with the membrane protein

K. Chattopadhyay, T. K. Das, A. Majumdar and S.  Mazumdar

J. Inorg. Biochem., (2002), 91(1), 116-124.

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Reaction of hydrogen peroxide and peroxidase activity in carboxymethylated cytochrome c: Spectroscopic and kinetic studies

S. Prasad, N.C. Maiti, S.  Mazumdar and S. Mitra

Biochim. Biophys. Acta, (2002), 1595(1), 64-76.

2001

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Steady state and time-resolved fluorescence studies on wild type high potential iron proteins; holo- and apo- forms

A.K. Sau, Chun-An Chen, J.A. Cowan, S.  Mazumdar and S. Mitra

Biophys. J., (2001), 81(4), 2320-2330.

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Interaction of surfactants with biomolecules and mimics

S.  Mazumdar

Handbook of Surfaces and Interfaces of Materials, (2001), Ed. H.C. Nalwa, Academic Press, Volume 5: Biointerfaces and Applications, Chapter 3 pp 73-128.

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Direct Observation of Release of Cytochrome c from Lipid Encapsulated Protein by Peroxide and Superoxide: A Possible Mechanism for Drug Induced Apoptosis

N. Das, S. Gupta and S.  Mazumdar

Biochem. Biophys. Res. Comm., (2001), 286(2), 311-314.

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pH induced conformational transition in the soluble CuA domain of Paracoccus denitrificans cytochrome oxidase

S. Gupta, A. Warne, M. Saraste and S. Mazumdar

Biochemistry,  (2001), 40, 6180-6189

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Direct Electrochemistry of Hemeproteins: Effect of electrode modification by neutral Surfactants

K. Chattopadhyay, and S.  Mazumdar

Bioelectrochemistry, (2001), 53, 17-24

2000

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Redox Linked Conformational Change in Bovine Heart Cytochrome c Oxidase: Picosecond Time-resolved Fluorescence Studies of the Cyanide Complex

T. K. Das and S.  Mazumdar

Biopolymers: Biospectroscopy,  (2000), 57,  316-322

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Binding of camphor to Pseudomonas putida cytochrome P450cam : Steady state and picosecond time-resolved fluorescence studies

S. Prasad, S.  Mazumdar and S. Mitra

FEBS Letts., (2000), 477, 157-160.

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Effect of adriamycin on the boundary lipid structure of cytochrome c oxidase: Picosecond time-resolved fluorescence depolarization studies

T. K. Das and S.  Mazumdar

Biophys. Chem., (2000), 86, 15-28

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Structural and Conformational Stability of Horseradish Peroxidase: Effect of Temperature and pH

K. Chattopadhyay and S.  Mazumdar

Biochemistry, (2000) 39(1), 263-270.

1999

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Direct electrochemical oxidation of horseradish peroxidase: Cyclic Voltammetric and spectroelectrochemical studies

K. Chattopadhyay and S.  Mazumdar

New J. Chem., (1999) 2, 137-139.

1998

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Unfolding pathway of cytochrome c oxidase induced by ionic surfactants: Circular dichroism and picosecond time-resolved fluorescence studies

T. K. Das & S.  Mazumdar

Proc. Ind. Acad. Sci. (Chem. Sc.), (1998), 110, 479-490. 

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J- and H- aggregate of Porphyrins with Surfactants: Fluorescence, Stopped-flow and Electron-microscopic Studies (Invited Article)

N.C. Maiti, S.  Mazumdar and N. Periasamy

J. Porphyrins and Phthalocyanins,  (1998), 2, 369- 376.

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Characterization of a partially unfolded structure of  cytochrome c    induced by sodium dodecyl  sulphate and the kinetics of its refolding

T.K Das, S.  Mazumdar and S. Mitra

Eur. J. Biochem., (1998),  254, 662-670.

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J- and H- aggregate of porphyrin-surfactant complexes: Time-resolved fluorescence and other spectroscopic studies.

N. C. Maiti, S.  Mazumdar and N. Periasamy

J. Phys. Chem. B,  (1998), 102, 1528-1538.

1997

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Dielectric relaxation study of glycine and valine in water mixture using picosecond time domain reflectometry

M.P. Lokhande, S. Mazumdar and S.C. Mehrotra

Ind. J. Biochem. Biophys., (1997), 34, 385-390.

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Direct electrochemistry of heme undecapeptide in aqueous micellar solutions: the effect of hydrophobicity and axial ligation on redox potential of heme.

K. Chattopadhyay and S.  Mazumdar

Current Science, (1997), 73, 65-68.

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Steady state and picosecond time-resolved fluorescence studies on recombinant Bacillus megaterium cytochrome P450 heme domain.

K.K. Khan, S.  Mazumdar, S. Modi, M.J. Sutcliffe, G.C.K. Roberts and S. Mitra    

Eur. J. Biochem., (1997),  244, 361-370.

1996

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Controlled J-aggregation of porphyrins by cationic surfactants.

N. C. Maiti, S.  Mazumdar and N. Periasamy      

Current Science, (1996), 70, 997-999.

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Spectroscopic and mechanistic studies of type-1 and type -2 copper sites in Pseudomonas aeruginosa azurin as obtained by addition of external ligands to mutant His46Gly.

G. van Pounderoyen, C.R. Andrew, T.M. Loehr, J. Sanders-Loehr, S.  Mazumdar, H.A.O. Hill and G.W. Canters

Biochemistry, (1996), 35, 1397-1407.

1995

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Selective denaturation of cytochrome c oxidase by ionic surfactants: depletion of both the heme a residues from the enzyme.

T. K. Das and S.  Mazumdar   

Current Science ,  (1995),  69, 874-876.

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Fluorescence Dynamics of Non-covalently linked porphyrin dimer and aggregates.

N. C. Maiti, M. Ravikanth, S.  Mazumdar, N. Periasamy 

J. Phys. Chem.,  (1995),  99, 17192-17197.

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Time-resolved fluorescence study of the single tryptophan in thiocyanate and azide derivatives of horseradish peroxidase: Implication for a pH-induced conformational change in the heme cavity.

T. K. Das and  S.  Mazumdar                                          

Proc. Indian Acad. Sci. (Chem. Sci.), (1995), 107, 505-518.

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Heme CD as a probe for monitoring local structural changes in heme proteins: Alkaline transition in hemeproteins.

T. K. Das,  S.  Mazumdar and S. Mitra    

Proc. Ind. Acad. Sci. (Chem. Sci.),  (1995),  107, 497-503.

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Conformational substates of apoprotein   of horseradish peroxidase in aqueous solution: A fluorescence dynamics study.

T. K. Das and   S.  Mazumdar

J. Phys. Chem.,  (1995), 99, 13283-13290.

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Dynamics of Porphyrin Molecules in Micelles: Picosecond Time-Resolved Fluorescence Anisotropy Studies.

N. C. Maiti,  S.  Mazumdar and N. Periasamy      

J. Phys. Chem.,  (1995), 99, 10708-10715.

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Ion-ion mutual neutralization if N2+ with F- and other fluorine containing negative ions.

S.V.K. Kumar,  S.  Mazumdar and S. K. Mitra          

Chem. Phys. Lett.,  (1995),  237, 448-455.

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pH-Induced Conformational Perturbation in Horseradish Peroxidase: Picosecond Tryptophan Fluorescence Studies on Native and Cyanide Modified Enzyme

T. K.i Das and  S.  Mazumdar

Eur. J. Biochem., (1995), 227, 823-828.

1994

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Conformation change due to reduction of cytochrome c oxidase in lauryl maltoside: pico second time resolved tryptophan fluorescence studies on the native and heat modified enzyme

T. K. Das and  S.  Mazumdar

Biochim. Biophys. Acta,  (1994), 1209, 227-237.

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The introduction of a negative charge in the hydrophobic patch of  Pseudomonas aeruginosa azurin affects the electron self exchange rate.

G. van Pounderoyen,  S.  Mazumdar, N. Hunt, H. A. O. Hill, G. W. Canters    

Eur.  J. Biochem.,  (1994),  222, 583-588. 

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Adenosine Triphosphate Synthesis Using an Electrochemically-driven Proton Pump

Petter J. Dobson, H.Allen O. Hill, Peter A. Leigh,  S.  Mazumdar and Alex Y.Safranov

J. Chem. Soc. (Chem. Comm.),   (1994), 807-808.

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Cytochrome c Oxidase: The unique enzyme at the terminal step of electron transfer in the respiratory chain.

S.  Mazumdar

Current Science,  (1994),  66(9), 650-655.

1993

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Time-resolved study of tryptophan fluorescence in vesicle reconstituted cytochrome oxidase: effect of redox transition.

T. K. Das and  S.  Mazumdar

FEBS Letts.,  (1993),  336(2), 211-214. 

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Binding of cyanide and thiocyanate to manganese reconstituted myoglobin and formation of peroxide compound: Optical spectral, multinuclear NMR and kinetic studies.

M. S. Mondal,  S.  Mazumdar and S. Mitra               

Inorg. Chem.,  (1993), 32, 5362-5367.

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Micelle-induced release of heme-NO from nitric oxide complex of myoglobin.

T. K. Das,  S.  Mazumdar and S. Mitra               

J. Chem. Soc. (Chem. Comm.),  (1993), 1447-1448.

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Biomimetic chemistry of hemes inside aqueous micelles             

S.  Mazumdar and S. Mitra

Structure and Bonding,  (1993),  81, 115-145.

1991

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Octaethyl porphyrinato  heme complexes encapsulated inside aqueous detergent micelles: NMR and optical spectral studies.

S.  Mazumdar                                                                        

J. Chem. Soc. (Dalton),  (1991), 2091-2096.

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Stability and characterization of iron(III) and iron(II) heme peptides encapsulated in aqueous detergent micelles:  1H NMR and UV-vis spectroscopic studies.

S.  Mazumdar, O. K. Medhi and S. Mitra                             

Inorg. Chem.,  (1991),  30, 700-705.


1990

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Proton nuclear magnetic resonance and optical spectra of six-co-ordinated high-spin (S=2) bis (tetrahydrofuran) (3,7,12,17-tetramethyl- 8,13- divinyl- porphyrin- 2,18- dipropionato) iron(II) encapsulated in aqueous detergent micelles.

S.  Mazumdar and O. K. Medhi                                             

J. Chem. Soc. (Dalton),   (1990), 2633-2636.

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1H and 13C NMR studies on the structure of micelles  encapsulating hemes in aqueous SDS solutions.

S.  Mazumdar                                                                                    

J. Phys. Chem.,  (1990),  94, 5947-5953.

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Low-spin iron(III) porphyrins encapsulated in aqueous  detergent micelles: 1 H and  15 N NMR studies.   

S.  Mazumdar, O. K. Medhi and S. Mitra                             

J. Chem. Soc. (Dalton),  (1990), 1057-1061.

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Aggregation in five coordinated high-spin hemins:  determination of solution structure by 1H NMR. 

S.  Mazumdar and S. Mitra                                                  

J. Phys. Chem.,   (1990),  94, 561-566.


1989

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On the quantal identification of low-lying electronic  states of CO2+

D. Mathur, V. R. Marathe and  S.  Mazumdar                       

J. Phys. B,  (1989), 22, L385-L389.

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How are S2+  ions formed in electron collisions with linear  S=C=S?

S.  Mazumdar, S. V. K. Kumar, V. R. Marathe and D. Mathur           

Rapid comm. in Mass. Spec., (1989), 3, 24-26.

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Proton NMR, optical spectra and magnetic properties of   four-coordinated intermediate-spin, five-coordinated high-spin and six-coordinated low-spin iron(II) hemes encapsulated in aqueous detergent micelles: model for hemoproteins.         

O. K. Medhi,  S.  Mazumdar and S. Mitra                             

Inorg. Chem.,  (1989), 28, 3243-3247.

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Electronic spectral study of the aqua = hydroxo   equilibrium of model iron(III) haems encapsulated in aqueous  detergent micelles. 

S.  Mazumdar, O. K. Medhi, N. Kannadaguili and S. Mitra  

J. Chem. Soc. (Dalton), (1989), 1003-1005.

1988

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The CS2  dication.                                                                               

S.  Mazumdar, V. R. Marathe, S. V. K. Kumar, and D.  Mathur

Int. J. Mass. Spec. and Ion Processes, (1988) 86, 351-355.

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Formation of doubly charged CO2+   ions: a combined  experimental and theoretical study.   

S.  Mazumdar, F. A. Rajgara, V. R. Marathe, C.  Badrinathan and D. Mathur.          

J. Phys. B: At. Mol. Opt. Phys., (1988), 21,  2815-2826.

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Excited states of XH2+  (X=C,N,O,S) ions: a combined experimental and theoretical study.            

M. Hamdam, S.  Mazumdar, V. R. Marathe, C. Badrinathan, A. G. Brenton and D. Mathur.     

J. Phys. B: At. Mol. Opt. Phys., (1988), 21,  2571-2584.

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Six-coordinated high-spin models for ferric hemoproteins:  NMR and ESR study of the diaquo(protoporphyrinatoIX) iron(III) cation and aquohydroxo (protoporphyrinatoIX) iron(III)   intercalated in aqueous detergent micelles.

S.  Mazumdar, O. K. Medhi and S. Mitra                              

Inorg. Chem., (1988), 27,  2541-2543.

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Proton nuclear magnetic resonance studies on haemin chloride in pyridine-water solution.   

S.  Mazumdar, L. B. Dugad, O. K. Medhi and S. Mitra         

J. Chem. Soc.(Dalton),  (1988), 2797-2802. 

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Electronic structure of synthetic iron(III) porphyrins in pyridine and pyridine-water solutions: a proton magnetic resonance study.

V. P. Shedbalkar, L. B. Dugad,  S.  Mazumdar and S. Mitra     

Inorg. Chim. Acta., (1988), 148, 17-20.


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