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Early life stress and programming psychiatric risk


What we experience as a child often has a lasting impression on our behaviour throughout the course of our life. Stressful and adverse experience during early life of an individual can often lead to a lasting vulnerability towards developing psychiatric disorders in adult life, a question particularly pertinent to the current times when depression has emerged as one of the greatest challenges to global health. In a recent study, the Vaidya lab has tested the idea via switching on the signaling pathway that leads to overactivation of excitatory neurons within the forebrain, using genetically engineered mice.


Early life stress and programming psychiatric risk