TIFR
Department of Chemical Sciences
School of Natural Sciences
  • Structure/Dynamics of Proteins and Fibrils from Solid State NMR

    Nuclear magnetic resonance spectroscopy of solid materials reveals structural and dynamics information. The methods make use of a combination of sample preparation, radiofrequency pulse sequence design, acquisition of multi-dimensional spectra techniques to get geometry information and structural elucidation…..

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  • Chemistry driven by delocalized molecular motions

    Chemical reactions are often conceptualized by making and breaking one bond at a time. The idea of localized bond alterations inhibits intuitive thinking about the structure as a whole. The Dasgupta group is focusing on creating a theme using collective motions existing in the molecular structure to drive selective and efficient chemistry...

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  • Tracking the molecular players in neurodegenerative disorders

    In the department of chemical sciences, we investigate biophysically tractable yet biologically interesting systems, using (mostly) spectroscopic and imaging tools, most of which we build ourselves. Our recent focus has been on two problems: protein misfolding/aggregation, and vesicular neurotransmission....

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  • Materials for Nanocatalysis

    We have developed new kind of fibrous silica nanospheres. The material exhibits excellent physical properties, including a high surface area, a fibrous surface morphology, good thermal and mechanical stability. Material was found to be very useful as a support for development of nano-catalysts and sorbents, wherein accessibility of active sites was increased significantly.

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  • Metabolomics for investigating disease process

    Malaria is considered to be one of the major killers in large part of the world. We believe, systems biological approaches may provide us specific insights to the mechanism of disease progression, since this involves the joint biological network of host and the parasite...

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About the Department

Scientists at the DCS explore the link between living systems and the physical laws that govern nature. They study molecules ranging in size as small as water and as large as a virus. The laws that govern interaction in molecules are best studied in well-defined and isolated small molecules. This information becomes applicable to design novel materials with exotic properties, of value to chemical and solar energy industries and to medical applications. To understand working of biological systems, studies are made on structure, dynamics and function of biological molecules. TIFR is a leader in state-of-the-art experimental techniques such as high field NMR, ultrafast lasers and single molecule methodologies.

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